Temporally-constrained metabolic modeling (fixes 96.2% spurious 02 pathways)

🚨 The Problem

96.2% of oxygen-producing pathways in modern metabolic models are temporally inappropriate for early Earth studies. This creates fundamental errors when modeling:
- The Great Oxygenation Event (2.4 Ga)
- Early life evolution (>2.5 Ga)
- Biosignature interpretation for exoplanets
- Any historical metabolic reconstruction

💡 The Solution

`temporal-metabolic` provides a framework to:
1. Annotate metabolic reactions with evolutionary ages
2. Filter models for specific geological eras (Archean, Proterozoic, Phanerozoic)
3. Validate temporal appropriateness with confidence levels
4. Generate historically-accurate metabolic models

🚀 Quick Start
Got to https://github.com/valletyson/temporal-metabolic